A 76-year-old woman, who had a history of treated hepatitis C virus infection, presented with rapidly progressive kidney failure and a stroke. Palpable purpura on the legs was noted. A diagnosis ...

The author describes the scientific foundations and implications of the results of a randomized, controlled trial of Mim8, a new mimetic of factor VIIIa, to treat hemophilia A.

Marston et al. (Jan. 29 issue)1 report that treatment with olezarsen in patients with severe hypertriglyceridemia substantially lowered triglyceride levels and was associated with ...

Guidelines recommend a trial of antiarrhythmic drugs before catheter ablation for persistent atrial fibrillation. Whether pulsed field ablation (PFA) may be a preferred initial treatment is ...

Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...

Artificial Intelligence has tremendous potential to advance clinical practice and the delivery of patient care.

Whether treatment with balanced crystalloid fluid leads to better outcomes than 0.9% saline in children treated for septic ...

Drug-overdose deaths among adolescents have increased in recent years. Steps can be taken to equip adolescents with the knowledge and tools they need to keep themselves safe.

Health worker burnout, exacerbated by Covid-19, is not only about long hours. It’s about the fundamental disconnect between health workers and the mission to serve that motivates them.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 9).

There has been substantial interest in the development of GLP-1 drugs and optimism about their public health effects. But some worrisome signals related to disordered eating have emerged.

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 10).